GAMMAGARD LIQUID is a ready-to-use liquid medicine that is given in a vein (intravenously) or under the skin (subcutaneously) to treat primary immunodeficiency (PI) in people 2 years and older.
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A partner you can trust to treat your PI
FOR 15+ YEARS—
the most prescribed immune globulin (IG)*
*Based on combined data: internal calculations by Takeda based on Marketing Research Bureau (MRB) database of total IG Units prescribed over a combined 15 years (between 2005 and 2022).
GAMMAGARD LIQUID is the most used treatment for PI, with over 15 years of real-world experience and over a million infusions.
*Based on combined data: internal calculations by Takeda based on Marketing Research Bureau (MRB) database of total IG Units prescribed over a combined 15 years (between 2005 and 2022).
What about effectiveness and safety?
GAMMAGARD LIQUID helped prevent infections, and most side effects were considered mild to moderate. Here are the results that showed how many infections and side effects were experienced by people in the study.
A study of 61 patients showed:
0 ASBIs
per patient-year*
There were no cases of validated acute serious bacterial infections (ASBIs) in patients treated with intravenous (IV) GAMMAGARD LIQUID.
*A patient-year is a patient experience in a clinical trial over the course of 1 year.
95% of the non-serious side effects were considered mild to moderate
381 of the 400 non-serious side effects reported in patients treated with IV GAMMAGARD LIQUID were considered mild (217) to moderate (164). The remaining 5% (19) were severe.
Side effects may occur with IV treatment. Please click below for more details about the most common side effects.
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IMPORTANT SAFETY INFORMATION and serious warnings regarding blood clots, decreased kidney function or kidney failure
What is the most important information that I should know about GAMMAGARD LIQUID?
GAMMAGARD LIQUID can cause the following serious reactions: severe allergic reactions causing difficulty in breathing or skin rashes; decreased kidney function or kidney failure; blood clots in the heart, brain, lungs or elsewhere in the body; severe headache, drowsiness, fever, painful eye movements, or nausea and vomiting; dark colored urine, swelling, fatigue, or difficulty breathing.
INDICATION
What is GAMMAGARD LIQUID?
GAMMAGARD LIQUID is a ready-to-use liquid medicine that is given in a vein (intravenously) or under the skin (subcutaneously) to treat primary immunodeficiency (PI) in people 2 years and older.
Important Safety Information
What is the most important information that I should know about GAMMAGARD LIQUID?
GAMMAGARD LIQUID can cause the following serious reactions:
- Severe allergic reactions causing difficulty in breathing or skin rashes
- Decreased kidney function or kidney failure
- Blood clots in the heart, brain, lungs or elsewhere in the body
- Severe headache, drowsiness, fever, painful eye movements, or nausea and vomiting
- Dark colored urine, swelling, fatigue, or difficulty breathing
Who should not use GAMMAGARD LIQUID?
Do not use GAMMAGARD LIQUID if you:
- Have had a severe allergic reaction to immune globulin or other blood products.
- Have a condition called selective (or severe) immunoglobulin A (IgA) deficiency.
What should I avoid while taking GAMMAGARD LIQUID?
- GAMMAGARD LIQUID can make vaccines (like measles/mumps/rubella or chickenpox vaccines) not work as well for you. Before you get any vaccines, tell your healthcare provider (HCP) that you take GAMMAGARD LIQUID.
- Tell your HCP if you are pregnant, or plan to become pregnant, or if you are nursing.
What are the possible or reasonably likely side effects of GAMMAGARD LIQUID?
GAMMAGARD LIQUID can cause serious side effects. If any of the following problems occur after starting GAMMAGARD LIQUID, stop the infusion immediately and contact your HCP or call emergency services:
- Hives, swelling in the mouth or throat, itching, trouble breathing, wheezing, fainting or dizziness. These could be signs of a serious allergic reaction.
- Bad headache with nausea, vomiting, stiff neck, fever, and sensitivity to light. These could be signs of irritation and swelling of the lining around your brain.
- Reduced urination, sudden weight gain, or swelling in your legs. These could be signs of a kidney problem.
- Pain, swelling, warmth, redness, or a lump in your legs or arms. These could be signs of a blood clot.
- Brown or red urine, fast heart rate, yellow skin or eyes. These could be signs of a liver or blood problem.
- Chest pain or trouble breathing, or blue lips or extremities. These could be signs of a serious heart or lung problem.
- Fever over 100°F. This could be a sign of an infection.
The following one or more possible reactions may occur at the site of infusion of GAMMAGARD LIQUID for PI, generally go away within a few hours, and are less likely after the first few infusions:
- Mild or moderate pain
- Swelling
- Itching
- Redness
- Bruising
- Warmth
During the infusion of GAMMAGARD LIQUID for PI, look out for the first signs of the following common side effects:
- Headache
- Migraine
- Fever
- Fatigue
- Itching
- Rashes/hives
- Cough
- Chest pain/tightness
- Chills/shaking chills
- Dizziness
- Nausea/vomiting
- Faster heart rate
- Upper abdominal pain
- Increased blood pressure
- Muscle cramps
- Sore throat
These are not all the possible side effects. Talk to your HCP about any side effect that bothers you or that does not go away.
For additional safety information including Warning about Blood Clots, Decreased Kidney Function, and Kidney Failure, click for Information for Patients and discuss with your HCP.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.