GAMMAGARD LIQUID is a ready-to-use liquid medicine that is given in a vein (intravenously) or under the skin (subcutaneously) to treat primary immunodeficiency (PI) in people 2 years and older.
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Let’s start at the beginning.
Why
GAMMAGARD LIQUID?
GAMMAGARD LIQUID
is a ready-to-use liquid
medicine.
- It contains immunoglobulin G, or IgG, to help protect against bacteria and viruses
- Medicine is received via intravenous (IV) or subcutaneous (subQ) infusions
- Both IV and subQ infusions temporarily increase antibodies
- Your doctor will help determine the best way to infuse
It’s also good to know that GAMMAGARD LIQUID has been used to treat primary immunodeficiency (PI) in children and adults for more than 15 years.
The most prescribed immune globulin (IG) therapy1
Doctors have prescribed GAMMAGARD LIQUID in the US for more than 15 years. (Based on combined data*)
16,000+
people infused
GAMMAGARD LIQUID
in 2023†
15+
years of real-world
experience
2,253,688
infusions†
*Internal calculations by Takeda based on Marketing Research Bureau (MRB) database of total IG Units prescribed over a combined 15 years (between 2005 and 2022).
†Calculations based on units of GAMMAGARD LIQUID sold from 2006-2023, assuming an average utilization of 450 g/yr/patient.
Not all IG therapies are the same.
GAMMAGARD LIQUID is made differently.
Free from sucrose or
added sugars
Free from glucose or
proline stabilizers*
Free from added
sodium
Free from added
preservatives
*Glycine serves as a stabilizing and buffering agent.
IV vs subQ: Let’s break down the two ways to infuse GAMMAGARD LIQUID.
There are different types of infusions, but you get the antibodies you need either way.
You can infuse intravenously, which means you get the IG you need into a vein. You’ll probably hear this referred to as an IVIG infusion.
You can infuse subcutaneously. This is referred to as a subQ infusion. You still get your infusions with a needle, but the needle goes into tissue under the skin, not into a vein.
Not sure which is right for you?
You and your doctor will decide what is best for you.
Take a look at this chart for some quick info about the different ways to infuse that could help guide your conversation with your doctor.
| IV | SubQ |
|---|---|
| Infused directly into the bloodstream through a vein | Infused under the skin in the fatty tissues of the abdomen, thighs, upper arm, or lower back |
| Infusions are done once every 3 to 4 weeks | Infusions are done once a week |
| Dose is given in 1 place on your body | Dose is given in multiple places on your body (the number of simultaneous sites should be limited to 8) |
| Infusions require a healthcare professional | Can be self-infused after you or a family member or friend receives training from a nurse |
| Infusions happen at a hospital, clinic, or at home with a nurse | Can be infused at home after being trained |
| Learn more about IV | Learn more about subQ |
For additional support on your PI treatment
journey, stay connected with emails.
IMPORTANT SAFETY INFORMATION and serious warnings regarding blood clots, decreased kidney function or kidney failure
What is the most important information that I should know about GAMMAGARD LIQUID?
GAMMAGARD LIQUID can cause the following serious reactions: severe allergic reactions causing difficulty in breathing or skin rashes; decreased kidney function or kidney failure; blood clots in the heart, brain, lungs or elsewhere in the body; severe headache, drowsiness, fever, painful eye movements, or nausea and vomiting; dark colored urine, swelling, fatigue, or difficulty breathing.
INDICATION
What is GAMMAGARD LIQUID?
GAMMAGARD LIQUID is a ready-to-use liquid medicine that is given in a vein (intravenously) or under the skin (subcutaneously) to treat primary immunodeficiency (PI) in people 2 years and older.
Important Safety Information
What is the most important information that I should know about GAMMAGARD LIQUID?
GAMMAGARD LIQUID can cause the following serious reactions:
- Severe allergic reactions causing difficulty in breathing or skin rashes
- Decreased kidney function or kidney failure
- Blood clots in the heart, brain, lungs or elsewhere in the body
- Severe headache, drowsiness, fever, painful eye movements, or nausea and vomiting
- Dark colored urine, swelling, fatigue, or difficulty breathing
Who should not use GAMMAGARD LIQUID?
Do not use GAMMAGARD LIQUID if you:
- Have had a severe allergic reaction to immune globulin or other blood products.
- Have a condition called selective (or severe) immunoglobulin A (IgA) deficiency.
What should I avoid while taking GAMMAGARD LIQUID?
- GAMMAGARD LIQUID can make vaccines (like measles/mumps/rubella or chickenpox vaccines) not work as well for you. Before you get any vaccines, tell your healthcare provider (HCP) that you take GAMMAGARD LIQUID.
- Tell your HCP if you are pregnant, or plan to become pregnant, or if you are nursing.
What are the possible or reasonably likely side effects of GAMMAGARD LIQUID?
GAMMAGARD LIQUID can cause serious side effects. If any of the following problems occur after starting GAMMAGARD LIQUID, stop the infusion immediately and contact your HCP or call emergency services:
- Hives, swelling in the mouth or throat, itching, trouble breathing, wheezing, fainting or dizziness. These could be signs of a serious allergic reaction.
- Bad headache with nausea, vomiting, stiff neck, fever, and sensitivity to light. These could be signs of irritation and swelling of the lining around your brain.
- Reduced urination, sudden weight gain, or swelling in your legs. These could be signs of a kidney problem.
- Pain, swelling, warmth, redness, or a lump in your legs or arms. These could be signs of a blood clot.
- Brown or red urine, fast heart rate, yellow skin or eyes. These could be signs of a liver or blood problem.
- Chest pain or trouble breathing, or blue lips or extremities. These could be signs of a serious heart or lung problem.
- Fever over 100°F. This could be a sign of an infection.
The following one or more possible reactions may occur at the site of infusion of GAMMAGARD LIQUID for PI, generally go away within a few hours, and are less likely after the first few infusions:
- Mild or moderate pain
- Swelling
- Itching
- Redness
- Bruising
- Warmth
During the infusion of GAMMAGARD LIQUID for PI, look out for the first signs of the following common side effects:
- Headache
- Migraine
- Fever
- Fatigue
- Itching
- Rashes/hives
- Cough
- Chest pain/tightness
- Chills/shaking chills
- Dizziness
- Nausea/vomiting
- Faster heart rate
- Upper abdominal pain
- Increased blood pressure
- Muscle cramps
- Sore throat
These are not all the possible side effects. Talk to your HCP about any side effect that bothers you or that does not go away.
For additional safety information including Warning about Blood Clots, Decreased Kidney Function, and Kidney Failure, click for Information for Patients and discuss with your HCP.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.